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Q.

Mark the correct statement about pro-insulin.

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a

Pro-insulin is a a fully mature and functional hormone.

b

Pro-insulin has 2 short polypeptide chains.

c

In humans, insulin is processed into pro-insulin.

d

Pro-insulin is like a pro-enzyme that needs to be activated.

answer is D.

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Detailed Solution

In mammals, including humans, insulin is synthesised as a pro-hormone (like a pro-enzyme, the pro-hormone also needs to be processed before it becomes a fully mature and functional hormone) which contains an extra stretch called the C peptide. This C peptide is not present in the mature insulin and is removed during maturation into insulin.

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