Match the following columns.

	Column-I (Actions)		Column-II (Hormones)
A	Reduces cellular glucose uptake	I	Cortisol
B	Hypoglycemic hormone	II	Aldosterone
C	Maintenance of electrolytes	III	Insulin
D	Anti-inflammatory responses	IV	Glucagon

Choose the correct answer from the options given below:

	A	B	C	D
1.	III	IV	II	I
2.	I	II	III	IV
3.	IV	III	II	I
4.	II	I	IV	III

Zona fasciculata of the adrenal cortex produces cortisol like glucocorticoids. Glucocorticoids stimulate gluconeogenesis, lipolysis and proteolysis, and inhibit cellular uptake and utilisation of amino acids. Cortisol is also involved in maintaining the cardio-vascular system as well as the kidney functions. Glucocorticoids, particularly cortisol, produces anti inflammatory reactions and suppresses the immune response. Cortisol stimulates RBC production.

Zona glomerulosa of the adrenal cortex produces mineralocorticoids. Corticoids, which regulate the balance of water and electrolytes in our body, are called mineralocorticoids. Aldosterone is the main mineralocorticoid in our body. Aldosterone acts mainly at the renal tubules and stimulates the reabsorption of Na⁺ and water and excretion of K⁺ and phosphate ions. Thus, aldosterone helps in the maintenance of electrolytes, body fluid volume, osmotic pressure and blood pressure.

The two main types of cells in the Islet of Langerhans are called α-cells and β-cells. The α-cells secrete a hormone called glucagon, while the β-cells secrete insulin.

Glucagon is a peptide hormone, and plays an important role in maintaining normal blood glucose levels. Glucagon acts mainly on the liver cells (hepatocytes) and stimulates glycogenolysis resulting in increased blood sugar (hyperglycemia). In addition, this hormone stimulates the process of gluconeogenesis, which also contributes to hyperglycemia. Glucagon reduces the cellular glucose uptake and utilisation. Thus, glucagon is a hyperglycemic hormone.

Insulin is a peptide hormone which plays a major role in the regulation of glucose homeostasis. Insulin acts mainly on hepatocytes and adipocytes (cells of adipose tissue), and enhances cellular glucose uptake and utilisation. As a result, there is a rapid movement of glucose from blood to hepatocytes and adipocytes resulting in decreased blood glucose levels (hypoglycemia). Insulin also stimulates conversion of glucose to glycogen (glycogenesis) in the target cells.