Match the following techniques or instruments with their usage:

 

(A)	Expression of insulin in E. coli	(I)	Phenotypic change in the host organism
(B)	lac z' gene	(II)	Heterologous gene expression
(C)	Aseptic conditions	(III)	Produces color in the presence of chromogenic substrate
(D)	Alteration of chemistry of DNA	(IV)	Enables exclusive growth of desired organisms

Select the correct option from following:

	A	B	C	D
1.	III	I	IV	II
2.	II	III	IV	I
3.	IV	III	I	II
4.	II	I	III	IV