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Q.

Maturation of proinsulin to insulin involves removal of 

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a

B peptide chain

b

D peptide chain

c

A peptide chain

d

C peptide chain

answer is B.

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Detailed Solution

Maturation of proinsulin into insulin takes place after removal C peptide. Proinsulin is an inactive and single polypeptide chain of the B and A subunits joined by the C-peptide region. On maturation, the C-chain splits off, resulting in formation of insulin molecule.

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