Mention any two autosomal genetic disorders with their symptoms.

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Detailed Solution

Down’s syndrome:

It is caused due to presence of extra chromosome in 21st set (Trisomy 21).
The affected individuals are with small head, partially open mouth, furrowed tongue.
Physical and intellectual development is slow.

Edward’s syndrome:

It is caused due to extra chromosome in 18^th set (Trisomy18).
It is more common in female offspring.
Majority die in foetal stage. Infant who survives has serious defects in heart and liver and die at early age.

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