muslims revere the prophet who was born in mecca.

Muslims revere the Prophet who was born in Mecca is the right answer.
The initial word of a sentence is always capitalised, according to the rule. All proper nouns in a sentence are capitalised. Religious names and terms, like all other words, must be capitalised. For example, God, Buddha, and so on.
As a result, according to the rules, Option 4 is the correct answer. The other selections are incorrect.