Nucleosome core is made up of  

The nucleosome core is made up of histone octamer which contains four types of eight histone proteins().

These proteins form a compact structure around which approximately 147 base pairs of DNA wrap, stabilizing the DNA and aiding in its organization. Histones are positively charged, which helps them interact with the negatively charged DNA backbone. Nucleosomes play a key role in gene regulation, DNA packaging, and maintaining the genome's stability. This structure allows chromatin to condense efficiently while still permitting access for transcription and replication.