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Q.

Nucleotides in RNA are joined by which of the following phosphodiester linkage?

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a

$5^{1}, 3^{1}$

b

$5^{1}, 2^{1}$

c

$3^{1}, 2^{1}$

d

$3^{1}, 3^{1}$

answer is A.

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Detailed Solution

A phosphodiester bond is a covalent bond that contains phosphate groups which are negatively charged. They make the backbone of the strands of nucleic acid. In both DNA and RNA, the phosphodiester bond is the linkage between 5’ carbon atom of one ribose sugar molecule and 3’ carbon atom of another ribose molecule in RNA and deoxyribose in DNA.

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