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Q.

Oxidative decarboxylation of pyruvate takes place in

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a

inner mitochondrial membrane 

b

matrix of mitochondria

c

cytoplasm 

d

perimitochondrial space 

answer is D.

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Detailed Solution

Oxidative decarboxylation of pyruvate takes place in the matrix of mitochondria. Pyruvate formed in cytosol enters the mitochondrial matrix and gets oxidatively decarboxylated by pyruvate dehydrogenase enzyme. Two molecules of NADH are produced from two molecules of pyruvate in the link reaction.

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