Oxidative decarboxylation of pyruvate takes place in

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cytoplasm

perimitochondrial space

inner mitochondrial membrane

matrix of mitochondria

answer is D.

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Detailed Solution

Oxidative decarboxylation of pyruvate takes place in the matrix of mitochondria. Pyruvate formed in cytosol enters the mitochondrial matrix and gets oxidatively decarboxylated by pyruvate dehydrogenase enzyme. Two molecules of NADH are produced from two molecules of pyruvate in the link reaction.

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