Ozone hole does not lead to which of the following issues?

The ozone hole is a thinning of the ozone layer in the stratosphere, which can lead to increased levels of harmful ultraviolet (UV) radiation reaching the Earth's surface. Exposure to UV radiation can cause a range of harmful effects on human health, including skin damage, eye damage, and an increased risk of skin cancer, but it is not known to cause ulcers in the intestine.

Ulcers in the intestine can be caused by a variety of factors, including infection with the bacterium Helicobacter pylori, long-term use of certain medications like nonsteroidal anti-inflammatory drugs (NSAIDs), excessive alcohol consumption, and smoking.