________________ pepsinogen changes into its active form.

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In the presence of hydrochloric acid

In the presence of trypsin

In the presence of bile

In the presence of carboxypeptidase

answer is A.

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Detailed Solution

Concept: In the stomach walls pepsin is stored and pepsinogen is a precursor of pepsin. It is activated in the form of pepsinogen.
The pepsinogen changes into its active form in the presence of hydrochloric acid.
Pepsinogen—HCL—>pepsin +Inactive peptide.
The pepsinogen is the digestive enzyme which helps in the process of the digestion of proteins. The hydrochloric acid secreted in the stomach gives the optimum pH, which activates the pepsinogen enzyme required to digest the proteins. The enzyme pepsinogen is converted to pepsin, which converts the proteins into amino acids.
Hence, 1 is the correct answer.

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