The size of VNTR varies in size from 0.1 to 20 kb as the numbers of repeats show very high degree of polymorphism. How can VNTR probes detect VNTRs of different people if there is so much variation in size?

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All the repeats contain the same sequence, and so we need only one probe.

We use probes of different lengths to test the samples of different people.

All samples are tested with the largest possible probe.

The probe is digested by enzymes in order to get different sizes.

answer is A.

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Detailed Solution

VNTRs are varying repeats at a specific location. VNTR probes are specific to the sequence of the repeats, not the size. So, a single probe with a single VNTR sequence is sufficient. It can bind to VNTRs of different lengths because all these contain at least one copy of the VNTR probe.

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