Read the following statements.
Statement A : Sickle-cell anaemia is a qualitative problem of synthesising an incorrectly functioning alpha globin.
Statement-B : Thalassemia is a quantitative problem of synthesising too few globin molecules.
In the light of given statements, choose the correct answer from the options given below.

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Statement A is true but B is false.

Statement A and B are true.

Statement A is false but B is true.

Statement A and B are false.

answer is C.

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Detailed Solution

Sickle-cell anaemia is a qualitative problem of synthesising an incorrectly functioning beta globin. The defect is caused by the substitution of glutamic acid (Glu) by valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule. The substitution of amino acid in the globin protein results due to the single base substitution at the sixth codon of the beta globin gene from GAG to GUG.

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