Q.

Read the following statements.

Statement I: Hormones which interact with intracellular receptors mostly regulate gene expression or chromosome function.

Statement II: Fat soluble hormones enter into the target cells.

In the light of given statements, choose the correct answer from the options given below.

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a

S-I is true, but S-II is false.

b

S-I is false, but S-II is true.

c

Both S-I and S-II are false.

d

Both S-I and S-II are true.

answer is D.

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Detailed Solution

  • Hormones that interact with intracellular receptors, such as steroid hormones (e.g., estrogen, testosterone, cortisol) and thyroid hormones (T3 and T4), often influence gene expression by binding to their respective receptors within the cell. This binding can lead to changes in gene transcription and protein synthesis, which in turn affect various cellular functions and responses.
  • Fat-soluble hormones, including steroid hormones, thyroid hormones, and retinoids, can easily cross the cell membrane due to their lipid-soluble nature. They enter the target cells directly and interact with intracellular receptors in the cytoplasm or nucleus. This is in contrast to water-soluble hormones, like peptide hormones, which typically interact with cell surface receptors and trigger second messenger pathways to elicit a cellular response.
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