Read the following. 

(i) Phenylketonuria causes mental retardation due to accumulation of _A_. 

(ii) __B__ is characteristic of Down Syndrome. 

(iii) Klinefelter males exhibit ___C__. In the above A, B, C represent.

	A	B	C
(1)	Phenyl pyruvates	Tall stature	Gynaeco mastism
(2)	Phenyl pyruvates	Palm crease	Breast development
(3)	Pyruvic acid	Reduced growth	Dyslexia
(4)	Ketones	Furrowed tongue	Short stature

Phenyl pyruvic acid and other derivatives are accumulated in brain results in mental retardation.

The individual affected with Down's syndrome is short statured with small round head, furrowed tongue and partially open mouth. Palm is broad with characteristic palm crease. Physical, psychomotor and mental development is retarded.

Klinefelter males exhibit the feminine development (development of breast, i.e., Gynecomastia) and such individuals will be sterile.