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Q.

Reduction in pH of blood will

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a

decrease the affinity of haemoglobin with oxygen

b

release bicarbonate ions by the liver

c

reduce the blood supply to the brain

d

 reduce the rate of heart beat

answer is A.

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Detailed Solution

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Reduction in pH of blood will decrease the affinity of haemoglobin with oxygen. Reduction of pH occurs when H+ concentration increases. When haemoglobin binds to H+, it unloads oxygen (Bohr effect) in the tissues,  low pO2, high pCO2, high H+ concentration (low pH) and higher temperature favour the dissociation of oxygen from the oxyhaemoglobin.

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