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Q.

SCID patients require a periodic infusion of genetically modified lymphocytes even in case of gene therapy because

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a

Lymphocytes are mortal

b

Retrovirus vector causes cancer

c

Lymphocytes are immortal

d

ADA cDNA is inactivated

answer is A.

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Detailed Solution

Lymphocytes are not immortal, the patient requires a periodic infusion of such genetically engineered lymphocytes.

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SCID patients require a periodic infusion of genetically modified lymphocytes even in case of gene therapy because