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Q.

Select the correct difference between sickle-cell anaemia and thalassemia.

 Sickle cell anaemiaThalassemia
1.Quantitative problemQualitative problem
2.Incorrectly functioning haemoglobin is synthesisedToo many haemoglobin molecules are synthesised
3.Controlled by two genesControlled by a single gene
4.Beta chain is affectedAlpha or beta chain is affected

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a

2

b

1

c

3

d

4

answer is D.

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Detailed Solution

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Thalassemia is of two types - alpha thalassemia and beta thalassemia depending on the globin chain affected.

Sickle cell anaemiaThalassemia
Qualitative problemQuantitative problem
Incorrectly functioning haemoglobin is synthesisedVery few haemoglobin molecules are synthesised
Controlled by a single gene (HBB)Controlled by two genes (HBA or HBB)
Beta chain is affectedAlpha or beta chain is affected
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