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ZIFT involves IVF to help women who cannot produce ovum to bear a child. In vitro fertilisation (IVF) is a procedure in which ova from the wife (or a donor female, if the wife cannot produce ova) and sperms from the husband/donor are collected and are induced to form zygote under simulated conditions in the laboratory.

GIFT involves in vivo fertilisation (in the fallopian tube) but not in vitro fertilisation.

ZIFT means zygote intrafallopian transfer. ZIFT is not possible if the woman has damaged Fallopian tubes.

There is no ovulation after menopause and a postmenopausal woman cannot bear a biological child.