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Select the correct order of sequencing of the human genome
a) arrangement of DNA fragments based on overlapping
b) isolation and breaking of DNA into fragments
c) DNA fragments are sequenced by automated DNA sequencers
d) construction of genetic and physical maps of the genome by collecting information about repetitive DNA sequences and DNA polymorphs.
e) cloning the DNA fragments in suitable hosts by using vectors BAC and YAC

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(a)→(e) → (c )→ (b) → (d)

(b)→(c) → (e)→ (a) → (d)

(b)→(e) → (c )→ (a) → (d)

(d)→(e) → (c )→ (a) → (b)

answer is D.

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Detailed Solution

(b) isolation and breaking of DNA into fragments;

(e) cloning the DNA fragments in suitable hosts by using vectors BAC and YAC;

(c ) DNA fragments are sequenced by automated DNA sequencers;

(a) arrangement of DNA fragments based on overlapping;

(d) construction of genetic and physical maps of the genome by collecting information about repetitive DNA sequences and DNA polymorphs.

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