Select the correct statement with respect to phenylketonuria.

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The effected individual lacks an enzyme that converts the amino acid tyrosine to phenylalanine.

It is an inborn error of metabolism which is inherited as an autosomal recessive trait.

Accumulation of tyrosine in brain results in mental retardation.

Tyrosine is converted into phenylpyruvic acid and other derivatives.

answer is B.

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Detailed Solution

Phenylketonuria is an inborn error of metabolism is also inherited as the autosomal recessive trait. The affected individual lacks an enzyme that converts the amino acid phenylalanine into tyrosine. As a result of this phenylalanine is accumulated and converted into phenylpyruvic acid and other derivatives. Accumulation of these in brain results in mental retardation.

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