Select the total number of correct statements about the loop of Henle.
(1) Descending limb is permeable to water.
(2) Descending limb is almost impermeable to electrolyte.
(3) Ascending limb is impermeable to water.
(4) It allows the transport of electrolyte only actively.
(5) At the tip of loop of Henle, the concentration of filtrate is 1200 m Osmol/L.
(6) It helps in the maintenance of high osmolarity in medullary interstitium.

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answer is D.

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Detailed Solution

The ascending limb is impermeable to water but allows transport of electrolytes actively or passively.

Reabsorption is minimum in its ascending limb. However, this region plays a significant role in the maintenance of high osmolarity of medullary interstitial fluid. The descending limb of loop of Henle is permeable to water but almost impermeable to electrolytes. This concentrates the filtrate as it moves down. The ascending limb is impermeable to water but allows transport of electrolytes actively or passively. Therefore, as the concentrated filtrate pass upward, it gets diluted due to the passage of electrolytes to the medullary fluid.

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