Sertoli cells are regulated by the pituitary hormone
A. LH
B. GH
C. FSH
D. Prolactin

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Detailed Solution

The anterior pituitary gland releases several important hormones, including:

Among these, FSH (Follicle Stimulating Hormone) plays a key role in both males and females:

Regulation by Hypothalamus: The hypothalamus releases GnRH (Gonadotropin-Releasing Hormone), which stimulates the anterior pituitary to secrete FSH.
In Males:
- FSH acts on Sertoli cells (nurse cells) in the testes.
- Sertoli cells release Androgen Binding Protein, which concentrates testosterone from Leydig cells.
- Testosterone is necessary for spermatogenesis (production of sperm).
- Sertoli cells also release Inhibin, which, along with testosterone, sends negative feedback to the hypothalamus to regulate further FSH release.
In Females:
- FSH stimulates follicle growth in the ovaries.
- During the follicular phase, FSH levels rise along with LH, leading to ovulation on the 14th day.
- FSH also helps the ovaries produce estrogen and progesterone.

Therefore, the correct answer is FSH.

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