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Q.

Sickle cell anemia is caused by a point mutation resulting in the change of an amino acid residue. Which change occurs in this condition?

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a

Aspartate to Glutamate

b

Valine to Glutamine

c

Glutamate to Valine

d

Lysine to Valine

answer is D.

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Detailed Solution

Glutamate is replaced by valine due to a point mutation ,GAG into GUG on mRNA. (A=T become T=A)

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Sickle cell anemia is caused by a point mutation resulting in the change of an amino acid residue. Which change occurs in this condition?