Skeletal muscle is severely affected by which of the following disorders?

Myasthenia gravis is a neuromuscular disorder that specifically affects skeletal muscles. It is characterised by muscle weakness and rapid fatigue, particularly in muscles that are under voluntary control. This weakness occurs because the body's immune system mistakenly attacks the neuromuscular junction. This autoimmune response results in the destruction or impairment of acetylcholine receptors on the muscle cells, preventing proper nerve stimulation of the muscles.