Statement A: The acid soluble pool represents roughly the cytoplasmic composition.
Statement B: Macromolecules from cytoplasm and organelles become acid insoluble fraction.

Statement A is true. The acid-soluble pool typically refers to the components within the cell, especially in the cytoplasm, that are soluble in acidic solutions.
Statement B is also true. When subjected to acidic conditions, certain macromolecules, especially those associated with structures like the cytoskeleton or cellular membranes, may become insoluble and form the acid-insoluble fraction.