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Q.

Statement –I : When O.T Avery, Mac Leod and Mc Carty treated S filtrate of Diplococcus pneumoniae with DNase and used for transformation of R strain into S strain the transformation did not occur.

Statement –II :In the transformation assay tests of O.T. Avery. Mac Leod and Mc Carty. DNase digested the transformation principle i.e., DNA.

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a

Statement I is true, Statement II is true

b

Statement I is false, Statement II is false

c

Statement I is true, Statement II is false

d

Statement I is false, Statement II is true

answer is A.

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Detailed Solution

Avery, Mac Leod, McCarty discovered that proteases and RNases did not affect transformation, so the transforming substance was not a protein or RNA. Digestion with DNase   did inhibit transformation, suggesting that the DNA caused the transformation. They concluded    that DNA is the hereditary material.

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