Statements related to human Insulin are given below.
Which statement(s) is / are correct about genetically engineered Insulin?
(a) Pro-hormone insulin contain extra stretch of C-peptide
(b) A-peptide and B-peptide chains of insulin were produced separately in E.coli, extracted and combined by creating disulphide bond between them.
(c) Insulin used for treating diabetes was extracted from cattle and pigs
(d) Pro-hormone insulin needs to be processed for converting into a mature and functional hormone.
(e) Some patients develop allergic reactions to the foreign insulin.
Choose the most appropriate answer from the options given below.

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(b) only

(c), (d) and (e) only

(a), (b) and (d) only

answer is A.

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Detailed Solution

Chains A and B are produced separately, extracted, and combined by creating disulphide bonds to form human insulin through genetic engineering.

Insulin extracted from cattle and pigs is not genetically engineered.

Genetically engineered insulin is produced by combining chain A and chain B, without the production of proinsulin.

Patients do not develop allergic reaction to genetically engineered insulin.

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