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Q.

Study the following.

a) Addison’s disease     

b) Grave’s disease

c) Myxoedema

d) Cretinism

Which of the above are autoimmune disorders?

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a

b and c

b

a and b

c

c and d

d

b and d

answer is B.

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Detailed Solution

  • Grave's disease is an autoimmune disorder where the immune system mistakenly attacks the thyroid gland, causing it to become overactive and produce excessive amounts of thyroid hormones. This leads to hyperthyroidism and a range of symptoms such as weight loss, rapid heart rate, nervousness, and bulging eyes (exophthalmos).
  • Addison's disease is an autoimmune disorder where the immune system attacks the adrenal glands, leading to insufficient production of adrenal hormones, including cortisol and often aldosterone.

The rest are not autoimmune disorders.

  • Myxoedema is a condition occurring due to  severe hypothyroidism, usually caused by thyroid gland dysfunction rather than an autoimmune process.
  • Cretinism refers to congenital hypothyroidism that occurs during fetal development or shortly after birth, often due to iodine deficiency. It's not primarily considered an autoimmune disorder.
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