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Q.

Study the following diagram showing the structure of proinsulin and select the option that correctly identifies the labels X, Y and Z.

Question Image
 XYZ
1.A peptideB peptideC peptide
2.C peptideB peptideA peptide
3.B peptideC peptideA peptide
4.C peptideA peptideB peptide

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a

1

b

2

c

3

d

4

answer is D.

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Detailed Solution

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X is C peptide; Y is A peptide and Z is B peptide. 

A peptide has an intrachain disulphide bond. So, Y can be identified as A chain. There are two interchain disulphide bonds between A chain and B chain. So, Z can be identified as B chain. X is the C chain that is removed during the maturation of proinsulin to insulin.

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Study the following diagram showing the structure of proinsulin and select the option that correctly identifies the labels X, Y and Z. XYZ1.A peptideB peptideC peptide2.C peptideB peptideA peptide3.B peptideC peptideA peptide4.C peptideA peptideB peptide