Q.

Study the pedigree chart given below and answer the questions that follow. 

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(a) On the basis of the inheritance pattern exhibited in this pedigree chart, what conclusion can you draw about the pattern of inheritance?
(b) If the female is homozygous for the affected trait in this pedigree chart, then what percentage of her sons will be affected?
(c) Give the genotype of offspring 1, 2, 3 and 4 in III generation.
OR
(c) In this type of inheritance pattern, out of male and female children which one has less probability of receiving the trait from the parents. Give a reason.

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Detailed Solution

(a) X-linked recessive trait
(b) All the sons (100%) will be affected because the sons receive X chromosomes only from the mother.
(c) 1. X (affected)Y, 

2. X(carrier)X, 

3. X(affected)Y 

4. XX (normal)

5. XX (normal)


OR

(c) A female has less probability of getting affected compared to a male. An affected daughter is born only if mother is a carrier and father is affected. 

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