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Q.

The pH of blood is 7.4. If the buffer in blood is CO2 and HCO3−, calculate the ratio of conjugate base to acid (H2CO3) to maintain the pH of the blood. Given K1 of H2CO3=4.5×10−7

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a

10.0

b

8.5

c

None of  these

d

11.25

answer is C.

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Detailed Solution

CO2+H2O⇌HCO3−+H+;

K1=[HCO3−][H+][CO2]=4.5×10−7

or [HCO3−][CO2]=4.5×10−7[H+]=4.5×10−74×10−8=11.25

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