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Q.

The Adenosine deaminase deficiency results into

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a

Addison’s disease

b

dysfunction of immune system

c

Parkinson’s disease

d

digestive disorder

answer is B.

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Detailed Solution

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Adenosine deaminase (ADA) deficiency is an inherited disorder that affects the immune system. ADA is an enzyme that plays a critical role in the development and function of T and B cells, which are important components of the immune system. In individuals with ADA deficiency, the lack of functional ADA enzyme leads to the accumulation of toxic metabolites that cause damage to lymphoid tissues and impair the development and function of T and B cells. This results in a weakened immune system that is unable to effectively fight off infections.
(1) Addison’s disease is due to the hyposecretion of glucocorticoid and mineralocorticoid hormones.
(3) Parkinson’s disease is a chronic, progressive neurological disorder that affects movement. It is caused by the
Degeneration of dopamine-producing neurons in the substantia nigra of the brain.
(4) ADA deficiency does not specifically cause any digestive disorder.

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