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Q.

The association of histone H₁ with a nucleosome indicates

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a

transcription is occurring

b

DNA replication is occurring

c

the DNA is condensed into chromatin fibre

d

the DNA double helix is exposed

answer is C.

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Detailed Solution

The association of H 1 histone with nucleosome indicates that DNA is condensed into chromatin fibre. In eukaryotes, DNA packaging is carried out with the help of histone proteins. Nucleosome is the unit of compaction. Its core consists of four pairs of histones (H2A, H2B, H3 and H4). The linker DNA, consisting of H1 histone connects two adjacent nucleosomes. These together constitute chromosome. It gives rise to a chromatin fibre after further condensation.

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