The coefficient of ${\mathrm{x}}^{301}$ in the expansion of $(1+\mathrm{x}{)}^{500}+\mathrm{x}(1+\mathrm{x}{)}^{499}+{\mathrm{x}}^2(1+\mathrm{x}{)}^{498}+...+{\mathrm{x}}^{500}$ is

Let $S=(1+\mathrm{x}{)}^{500}+\mathrm{x}(1+\mathrm{x}{)}^{499}+{\mathrm{x}}^2(1+\mathrm{x}{)}^{498}+...+{\mathrm{x}}^{500}$

This is sum of first 501 terms of Geometric progression whose first term is ${\left(1+x\right)}^{500}$ and the common ratio is $\frac{x}{1+x}$

We know that the sum of the first $n$ terms of Geometric progression whose first term is $a$ and common ratio $r$ is $S=\frac{a\left(1-r^n\right)}{1-r}$

Hence,

           $\begin{array}{rcl}S& =& \frac{{\left(1+x\right)}^{500}\left(1-{\left({\displaystyle \frac{x}{1+x}}\right)}^n\right)}{1-{\displaystyle \frac{x}{1+x}}}\\ & =& \frac{{\left(1+x\right)}^{500}{\displaystyle \frac{\left({\left(1+x\right)}^{501}-x^{501}\right)}{{\left(1+x\right)}^{501}}}}{{\displaystyle \frac{1}{1+x}}}\\ & =& \left({\left(1+x\right)}^{501}-x^{501}\right)\end{array}$

$\mathrm{S}=(1+\mathrm{x}{)}^{501}-{\mathrm{x}}^{501}$

The coefficient of $x^r$ in the expansion of ${\left(1+x\right)}^n$ is ${}^{n}C_r$

Hence, coefficient of ${\mathrm{x}}^{301}$ in S is $\boxed{{}^{501}C_{301}}$