The enzyme pyruvate dehydrogenase involved in the link reaction requires the participation of the following for its functioning.

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Mg ²⁺,NAD ⁺and CoA

Mg ²⁺,FAD ⁺and CoA

FAD⁺,Mn ²⁺only

Mg ²⁺,NAD ⁺only

answer is C.

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Detailed Solution

Link reaction is oxidative decarboxylation . During link reaction pyruvic acid undergoes oxidative decarboxylation and forms acetyl Co-A . Products formed in this reaction are CO2 and NADH.

The enzyme requires Mg ²⁺,NAD ⁺and CoA. Additionally it also requires thymine pyrophosphateTPP and lipoic acid.

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