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Q.

The permanent cure for ADA deficiency is

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a

infusion of genetically engineered erythrocytes into a patient

b

introduction of functional gene into the cells at embryonic stage

c

bone marrow transplantation

d

enzyme replacement therapy

answer is B.

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Detailed Solution

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ADA deficiency can be cured by bone marrow transplantation or by enzyme replacement therapy but both of these approaches are not considered permanent cure. If the gene isolated from marrow cells producing ADA is introduced into the cells at early embryonic stages, it could be a permanent cure.

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The permanent cure for ADA deficiency is