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Q.

The pH of blood stream is maintained by a proper balance of H2CO3 and NaHCO3  concentration. The volume of  10M NaHCO3 solution which is mixed with 10 mL sample of blood which is 4 M in  H2CO3 in order to maintain a pH of 7.4 is x mL. Ka for H2CO3  in blood is  4×107. What will be the value of  x10?

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answer is 4.

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Detailed Solution

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[H2CO3] in blood = 4M                      [NaHCO3]=10M
Volume of blood = 10 mL
Let the volume of  NaHCO3 used = x mL
[H2CO3]  in mixture  =4×10(x+10)
 [NaHCO3] in mixture=10×x(x+10) pH=pKa+logsaltacid 7.4=7-log4(10×x)(x+10)(x+10)(4×10)7.4=6.4+log10x40 log10x40=1  so 10x40=10 
  Hence  x10=4
 

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