The ${pK}_{a}$ of acetylsalicylrc acid (aspirin) is 3.5. The pH of gastric juice in human stomach is about 2-3 and the pH in the small intestine 1s about 8. Aspirin will be:

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ionised in the stomach and almost unisoni.sed in the small intestine

completely ionised in the small intestine and in the stomach

ionised in the stomach and almost unionised in the small intestine

unionised in the small intestine and in the stomach

answer is D.

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Detailed Solution

In the small intestine, bases can react with aspirin, however, human stomach is relatively acidic, hence, cannot ionise aspirin.

So, ionised in the stomach and almost unionised in the small intestine

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