Thin segment of ascending limb of Henle’s loop allows

The thin segment of the ascending limb of Henle's loop does not play a significant role in the transport of urea into the tubule from the medullary interstitium. Instead, urea transport primarily occurs in the inner medullary collecting ducts and is regulated by the hormone antidiuretic hormone (ADH).

The thin segment of the ascending limb of Henle's loop is impermeable to water and ions, and it actively transports sodium and chloride ions out of the tubule, contributing to the establishment of the concentration gradient in the medulla. Urea transport, on the other hand, primarily occurs in the inner medullary collecting ducts under the influence of ADH. ADH increases the permeability of the collecting ducts to water and urea, allowing both substances to be reabsorbed from the filtrate back into the bloodstream.