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Q.

Transplantation of tissues/organs fails often due to non­ acceptance by the patient's body. Which type of immune response is mainly responsible for such rejections?

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a

Cell-mediated immune response

b

Autoimmune response

c

Hormonal immune response

d

Innate immune response

answer is A.

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Detailed Solution

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When the immune system recognizes the transplanted tissue as ‘foreign’ it mounts an immune response that can result in rejection of the transplanted tissue/organ. The rejection is mainly due to cell-mediated immune responses.
(2) Hormonal immune response and physiological immune response is not a recognized term in immunology.
The immune system does not have a specific hormonal response to transplanted tissues/organs.
(3) Innate immune system does not have a specific physiological response to transplanted tissues/organs.
(4) Autoimmune response involves the immune system attacking the body’s own tissues. Graft rejection is related to foreign tissues/organs.

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