Two charges $Q_1 and Q_2$ have their respective placements at the inside and the outside of a closed surface $S$. If $E$ be the field at any point on $S$ and $\varphi$ be the flux of $E$ over the surface $S$, then if

E depends upon both$Q_1 and Q_2$ but $\varphi$depends only on $Q_1$ because according to Gauss law flux from any surface depends only on the charge enclosed by that surface.

so if ${\mathrm{Q}}_1$ changes, both $\mathrm{E}$ and $\varphi$will change.

${\mathrm{Q}}_2$ changes, then $\mathrm{E}$will change and $\varphi$ remains same.

${\mathrm{Q}}_1=0,$ $\varphi is zero$and $\mathrm{E}$is non zero.

Hence the correct answer is 1,2,3