Under secretion of GH leads to

Over-secretion of GH stimulates abnormal growth of the body leading to gigantism and low secretion of GH results in stunted growth resulting in pituitary dwarfism. Excess secretion of growth hormone in adults especially in middle age can result in severe disfigurement (especially of the face) called acromegaly, which may lead to serious complications, and premature death if unchecked.