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What are transformants and non-transformants?

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Detailed Solution

Transformants are cells that successfully take up and express foreign DNA, while non-transformants are cells that do not take up foreign DNA.

Transformants: Cells showing new traits because they received and integrated external DNA during transformation.
Non-Transformants: Cells that fail to take in DNA, thus remaining unchanged.

Examples in Biotechnology

Bacteria receiving a plasmid with antibiotic resistance gene = transformants.
Bacteria without plasmid uptake = non-transformants.

Importance

Helps in genetic engineering experiments.
Used in cloning, insulin production, and recombinant DNA technology.

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