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Q.

What enzyme does HIV use to convert RNA to DNA

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a

DNA gyrase

b

RNA polymerase

c

Reverse transcriptase

d

DNA helicase

answer is C.

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Detailed Solution

HIV (Human Immunodeficiency Virus) uses the enzyme reverse transcriptase to convert its RNA into DNA.

  • How It Works:
    1. HIV is an RNA virus, specifically a retrovirus.
  • 2. After entering a host cell (usually a CD4+ T-cell), the viral RNA genome is released.
  • 3. Reverse transcriptase then converts the single-stranded viral RNA into double-stranded DNA.
  • 4. This newly synthesized viral DNA is integrated into the host cell’s DNA using another enzyme called integrase.

Key Points:
1. Enzyme name: Reverse Transcriptase

2. Function: RNA → DNA (reverse of normal transcription in cells)

3. Why it matters: This step is crucial for HIV’s ability to hijack the host cell and replicate, making reverse transcriptase a major target for antiretroviral drugs.

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