What is the affinity of the pigment combining with O₂when the P₅₀ Value of hemoglobin rises?

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Remains the same

Rises

Falls

First rises and then falls

answer is C.

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Detailed Solution

The oxygen-hemoglobin dissociation curve describes the relationship between hemoglobin saturation and oxygen partial pressure. The P₅₀ value of hemoglobin is the oxygen partial pressure at which hemoglobin is 50% saturated.

When the P₅₀value of hemoglobin rises, it indicates that hemoglobin has a lower affinity for oxygen, which causes the dissociation curve to shift to the right. This indicates that hemoglobin's oxygen saturation decreases at a given oxygen partial pressure.

Therefore, when the P₅₀ value of hemoglobin rises, the affinity of the pigment combining with O₂ falls.

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