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Q.

What is the function of GnRH in males?

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a

Stimulates Leydig cells to secrete androgens

b

Stimulates the synthesis and secretion of FSH and LH

c

Acts on the central neural system and influence the libido

d

Promotes testicular descent into the scrotum during foetal stage

answer is B.

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Detailed Solution

GnRH stimulates the anterior pituitary gland to synthesise the gonadotropins (FSH and LH) in both males and females.

  • Leydig cells are influenced by LH.
  • Testosterone is responsible for male secondary sexual characteristics and libido.
  • Complete testicular descent is essential for normal testicular function in adult life. This process depends on the growth and reorganisation of gubernacula, regulated by hormones like insulin-like peptide 3 (INSL3) and testosterone. Proper testicular position in the scrotum is crucial for sperm production and reproductive health.
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