What is the genetic basis of blood types in ABO system in man?

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Detailed Solution

The gene for ABO blood grouping system is ‘I’. It has three types of alleles namely I^A , I^B and I^O.
So, the possible genotypes are six types for four phenotypes as given below.

Phenotypes of blood group	Possible genotypes
A	$I^{A} I^{A}, I^{A} O^{O}$
B	$I^{B} I^{B}, I^{B} I^{O}$
AB	$I^{A} I^{B}$
O	$I^{O} I^{O}$

The expression $n \frac{(n + 1)}{2}$ can be used to know the number of kinds of genotypes of the ABO system where n = number of alleles.

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