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Q.

What is the purpose of a channel protein?

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Detailed Solution

A channel protein forms a tiny tunnel in a cell membrane that lets specific ions or water pass quickly down their concentration gradient without using energy.

Where channel proteins sit and why they matter

Channel proteins are embedded in the phospholipid bilayer of cell membranes. The bilayer blocks charged particles because its interior is oily (hydrophobic). Channel proteins solve this problem by providing a watery passage. This safe passage allows cells to control their inner environment—balancing salt, pH, electrical signals, and water flow—so life processes can run smoothly.

How channel proteins work (simple steps)

  1. Selectivity: The channel’s shape and charged amino acids select particular ions (e.g., Na+, K+, Ca2+, Cl) or water (aquaporins).
  2. Gating: Many channels open or close in response to signals—voltage changes, chemicals (ligands), or mechanical stretch.
  3. Passive transport only: Particles move from high concentration to low concentration or along an electrical gradient. No ATP is spent by the channel itself.

Key types and examples

Channel typeTrigger (gate)Example function
Voltage-gatedMembrane voltageAction potentials in neurons (Na+, K+ channels)
Ligand-gatedChemical bindingNeurotransmitter-controlled synapses (e.g., acetylcholine receptor)
Mechanically gatedStretch/pressureTouch and hearing receptors
AquaporinsUsually openFast water movement in kidneys and plant cells

Channel vs. carrier proteins (quick comparison)

FeatureChannel proteinCarrier protein
Transport speedVery fast (many ions/sec)Slower (one/few molecules per cycle)
Energy usePassive onlyPassive or active (some use ATP)
MechanismOpen pore/tunnelShape changes carry molecules across

Why they are essential

  • Nerve signals and muscle contraction: Rapid ion movement creates electrical activity and triggers contraction.
  • Water balance: Aquaporins prevent cells from swelling or drying out.
  • Homeostasis: Channels help keep pH and salt levels right for enzymes to work.
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