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Q.
What is the purpose of a channel protein?
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Detailed Solution
A channel protein forms a tiny tunnel in a cell membrane that lets specific ions or water pass quickly down their concentration gradient without using energy.
Where channel proteins sit and why they matter
Channel proteins are embedded in the phospholipid bilayer of cell membranes. The bilayer blocks charged particles because its interior is oily (hydrophobic). Channel proteins solve this problem by providing a watery passage. This safe passage allows cells to control their inner environment—balancing salt, pH, electrical signals, and water flow—so life processes can run smoothly.
How channel proteins work (simple steps)
- Selectivity: The channel’s shape and charged amino acids select particular ions (e.g., Na+, K+, Ca2+, Cl−) or water (aquaporins).
- Gating: Many channels open or close in response to signals—voltage changes, chemicals (ligands), or mechanical stretch.
- Passive transport only: Particles move from high concentration to low concentration or along an electrical gradient. No ATP is spent by the channel itself.
Key types and examples
Channel type | Trigger (gate) | Example function |
Voltage-gated | Membrane voltage | Action potentials in neurons (Na+, K+ channels) |
Ligand-gated | Chemical binding | Neurotransmitter-controlled synapses (e.g., acetylcholine receptor) |
Mechanically gated | Stretch/pressure | Touch and hearing receptors |
Aquaporins | Usually open | Fast water movement in kidneys and plant cells |
Channel vs. carrier proteins (quick comparison)
Feature | Channel protein | Carrier protein |
Transport speed | Very fast (many ions/sec) | Slower (one/few molecules per cycle) |
Energy use | Passive only | Passive or active (some use ATP) |
Mechanism | Open pore/tunnel | Shape changes carry molecules across |
Why they are essential
- Nerve signals and muscle contraction: Rapid ion movement creates electrical activity and triggers contraction.
- Water balance: Aquaporins prevent cells from swelling or drying out.
- Homeostasis: Channels help keep pH and salt levels right for enzymes to work.
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