What is true w.r.t. prosthetic group in an enzyme?

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It serves as the primary substrate for the enzyme's catalytic action.

It temporarily associates with the apoenzyme during catalysis.

It is a temporarily associated metal ion that activates the enzyme.

It is tightly bound to the apoenzyme and is part of the enzyme's active site.

answer is C.

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Detailed Solution

Prosthetic groups are organic compounds and are distinguished from other cofactors in that they are tightly bound to the apoenzyme. For example, in peroxidase and catalase, which catalyze the breakdown of hydrogen peroxide to water and oxygen, haem is the prosthetic group and it is a part of the active site of the enzyme.

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